Urinary Tract Infection Molecular Testing Kit
UTI KIT
The UTI comprehensive kit detects, by Molecular Technique, urinary pathogens. Our testing is completed with high sensitivity and specificity compared to the traditional urine culture technique. We identify pathogens that are difficult to grow in a culture while using the largest pathogen menu available.
COLLECTION & TESTING PROCESS
- Estimate the quantity of normal vaginal flora and compare with pathogenic species
- Detect ten pathogenic species causing bacterial vaginosis
- Provide the results in text and graphical format
- Provide suggestive treatment of BV based on the results
- Monitor the efficacy of antimicrobial therapy
- Can detect Aerobic vaginitis, candidiasis
ACCURACY AND QUICK RESULTS
Now your lab can provide healthcare providers with the quickest and most accurate results possible to allow them to determine an accurate diagnosis:
- Expedited patient results
- Drug resistance marker results available prior to antibiotic sensitivity results
- Traditional antibiotic sensitivity results accompany UTI results
- Individual pathogen test ordering available
- Direct access to experience scientific staff
- Personal customer service experience
For Research Use Only. Not for use In diagnostic procedures.
Pathogens Detected in the DTPM UTI Molecular Testing Kit:
Pathogen | Strain(s) Identified* | Target Gene | GenBank Accession Number | Amplicon1 (base pairs) | BLAST Score2 Range (High/Low) | Sequences3 Reviewed | Matches4 (True Positives) | Specificity5 |
---|---|---|---|---|---|---|---|---|
Candida albicans | Candida albicans, Candid dubliniensis | Erg11 | NC_032093 | 74 | 142/134 | 1.02E+08 | 363 | 100% |
Candida parapsilosis | Candida parapsilosis | Erg11 | NW_023503279 | 65 | 130/130 | 1.02E+08 | 502 | 100% |
Candida tropicalis | Candida tropicalis | Erg11 | NW_003020060 | 70 | 140/134 | 1.02E+08 | 369 | 100% |
Enterobacter cloacae/hormaechei | Enterobacter cloacae, E. hormaechei, E. roggenkampii, E. asburiae, E. ludwigii, E. kobei, E. bugandensis | apbC | NZ_CP009756 | 72 | 138/133 | 1.02E+08 | 748 | 100% |
Enterococcus faecalis | E faecalis | recG | NZ_CP091198 | 66 | 132/122 | 1.02E+08 | 619 | 100% |
Escherichia coli / Shigella | Escherichia coli, O55H7, O157:H7, O10:H32, O104:H4, O121:H19, O178:H19, O6:H16, O169:H41, O25:H16, O27:H7, O128:H27, O114:H49, O15:H11, O6:H16, O127:H6, O4:H5, 025:H1, O8:H28, O170:H18, 085:H1, 0158:H24. Shigellla boydii, S. flexneri, S. dysenteriae | lacY | NC_000913 | 75 | 147/137 | 1.02E+08 | 4629 | 100% |
Klebsiella oxytoca | Klebsiella oxytoca, K grimontii, K michiganensis, Raoultella terrigena | TonB | NZ_CP033844 | 60 | 117/112 | 1.02E+08 | 179 | 100% |
Klebsiella pneumoniae | Klebsiella variicola, Klebsiella quasipneumoniae, Klebsiella africana | gyrA | NC_016845 | 57 | 114/105 | 1.02E+08 | 3138 | 100% |
Klebsiella pneumoniae | Klebsiella pneumoniae, K variicola, K quasipneumoniae, K africana | gyrA | NC_016845 | 57 | 114/107 | 1.02E+08 | 3189 | 100% |
Morganella moranii | Morganella moranii | gyrA | CP014026 | 65 | 130/120 | 1.02E+08 | 63 | 100% |
Mycoplasma hominis | Micoplasma hominis, Metamycoplasma hominis | KtrB | CP009652 | 79 | 158/153 | 1.02E+08 | 21 | 100% |
Nakaseomyces glabratus [previously Candida glabrata] | Nakaseomyces glabratus previously known as Candida glabrata | Erg11 | NC_006028 | 64 | 128/128 | 1.02E+08 | 101 | 100% |
Proteus mirabilis | Proteus mirabilis | gyrA | NC_010554.1 | 61 | 122 | 1.02E+08 | 143 | 100% |
Providencia stuartii | Providencia stuartii | RecA/RadA | CP003488 | 64 | 128 | 1.02E+08 | 20 | 100% |
Psuedomonas aeruginosa | Psuedomonas aeruginosa, P. alcaligenes, P. balearica, P. citronellolis, P. furukawaii, P. fluorescens, P. guangdongensis, P. jinjuensis, P. knackmussii, P. lalkuanensis, P. multiresinivorans, P. nitroreducens, P. otitidis, P. oryzihabitans, P. stutzeri, P. tohonis, P. paraeruginosa, Stutzerimonas balearica, S. frequens, S. stutzeri | oprL | NC_002516.2 | 60 | 120/90 | 1.02E+08 | 2035 | 100% |
Serratia spp V2.0 | Serratia marescens, S. bockelmannii, S. entomophila, S. ficaria, S. grimesii, S. liquefaciens, S. nematodiphila, S. odorifera, S. plymuthica,S. proteamaculans, S. quinivorans, S. surfactantfaciens, S. symbiotica, S. ureilytica, S rubidaea | gyrA | NZ_CP027798 | 66 | 120/109 | 1.02E+08 | 1333 | 100% |
Staphylococcus aureus | Staphylococcus aureus | acetyl-CoA acetyltransferase | NC_007795 | 59 | 112/107 | 1.02E+08 | 1912 | 100% |
Staphylococcus aureus | Staphylococcus aureus | acetyl-CoA-acetyltransferase | NC_007795 | 59 | 112/104 | 1.02E+08 | 1969 | 100% |
Staphylococcus saprophyticus | Staphylococcus saprophyticus | KtrB | NZ_CP014113 | 66 | 132 | 1.02E+08 | 25 | 100% |
Streptococcus agalactiae | Streptococcus agalactiae | gyrA | CP003919 | 72 | 141/136 | 1.02E+08 | 216 | 100% |
Ureaplasma urealyticum | Ureaplasma urealyticum | ureC | NC_011374 | 75 | 150 | 1.02E+08 | 8 | 100% |
Footnotes:
- The Amplicon is the amplified piece of DNA which contains the Fwd, Rev and Probe sequence. Sequence between the Fwd, Rev and Probe are also included in Amplicon.
- The BLAST Score describes how similar the Amplicon sequence is to aligned sequences in the non-redundant GenBank Database. The range shown as High/Low reflects the highest and lowest scores for a pathogen that would generate a positive response using this assay.
- The number of sequences reviewed reflect the total number sequences in the non-redundant GenBank database on the date of the analysis. This number will change as new sequences are added to the GenBank database.
- Matches reflect the total number of pathogens identified in the BLAST search that would generate a positive ressponse. Statistically these are the number of True Positives (the diagnostic test would indicates the presence of the correct disease) = TP
- False positive (FP) – Test incorrectly detects the presence of pathogen in a sample that does not contain the pathogen. Shown as an incorrect pathogen in the BLAST analysis with a Score within the High/Low range listed for the assay.
True negative (TN) – Test correctly identifies absence of pathogen. Calculated from BLAST data as the (total number of sequences reviewed) – (total number of pathogens correctly detected or TP).
Specificity = TN / TN + FP
https://lexjansen.com/nesug/nesug10/hl/hl07.pdf
* If you have inquiries about specific strains, please contact DTPM support.