Pharyngitis Molecular Testing Kit

PHARYNGITIS KIT

Pharyngitis is inflammation of the pharynx, which is in the back of the throat. It is most often referred to simply as a “sore throat.” Pharyngitis can also cause scratchiness in the throat and difficulty swallowing.
Our pharyngitis kit is a comprehensive kit detecting, by molecular technique, the most common pathogens infecting the throat.

SYMPTOMS TO CONSIDER:

  • A red throat
  • Runny or stuffy nose
  • Dry cough
  • Hoarseness
  • Redness of the eyes

ACCURACY AND QUICK RESULTS

Now your lab can provide healthcare providers with the quickest and most accurate results possible to allow them to determine an accurate diagnosis:

  • Expedited patient results
  • Multiple pathogens available
  • Unmatched accuracy of PCR
  • Simple collection
  • Direct access to experience scientific staff
  • Personal customer service experience

For Research Use Only. Not for use In diagnostic procedures.

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Pathogens Detected in the DTPM Pharyngitis Molecular Testing Kit:

Strain(s) Identified* Target Gene GenBank Accession Number Amplicon1 (base pairs) BLAST Score2 Range (High/Low) Sequences3 Reviewed Matches4 (True Positives) Specificity5
Adenovirus 3, 4, 4a, 4p. 7, 10, 11, 13, 14, 16, 17, 21, 21a, 34, 35, 40, 48, 50, 51, 55, 71, B3, E4, E4, Human mastadenovirus B, D, E L3 NC_011203 59 100/90 1.02E+08 1637 100%
Human coronavirus 229, Bat coronavirus N NC_011204 74 148/132 100574661 241 1
Human coronavirus HKU-1 N NC_011205 78 147/142 100574661 143 1
Human coronavirus NL-63 N NC_011206 67 134/129 100574661 226 1
Human coronavirus OC43, Bovine, Dromedary camel , Canine, Yak, Deer (Water, White-tailed ), Waterbuck, Giraffe, Sable antelope, Porcine, Rabbit N NC_011207 65 130/108 100574661 955 1
H3N2, H1N1, H5N1, H3N2, H1(2009), H7N9 [inquire about other strains] M1/M2 NC_011208 98 161/129 1.02E+08 54079 100%
B/Victoria, B/Yamagata NEP NC_011209 66 126/116 1.02E+08 7064 100%
HPV 1, Human respirovirus 1 L RNA polymerase NC_011210 74 142/132 1.02E+08 114 100%
HPV 3, Human respirovirus 3 N NC_011211 75 141/131 1.02E+08 580 100%
HPV 4, Human parainfluenza virus 4a & 4b, Human orthorubulavirus 4 HN NC_011212 118 188/141 1.02E+08 157 100%
Human Rubelavirus 2, Human orthorubelavirus 2 NP NC_011213 68 124 1.02E+08 83 100%
A,B, Human orthopneumovirus L NC_011214 125 214/199 1.02E+08 5343 100%
Rhino A, B, C: Enterovirus D68, A23, A47, A71, Coxsackievirus A1, A6, A11, A13, A16, A20, A22, Echovirus, Human poliovirus 1, 2, 3, *Pathogens associated with hand, foot, and mouth disease (Coxsackievirus A16, A6, Enterovirus 71) are detected by this assay Polyprotein NC_011215 114 171/98 1.02E+08 7798 100%
Chlamydia pneumoniae [previously known as Chlamydophila pneumoniae] porin NC_011216 66 132/112 1.02E+08 33 100%
Streptococcus agalactiae gyrA NC_011217 72 141/136 1.02E+08 216 100%
Streptococcus dysgalactiae gyrA NC_011218 56 112/103 1.02E+08 62 100%
Streptococcus pneumoniae lytA NC_011219 60 120/110 1.02E+08 375 100%
Streptococcus pyogenes gyrA NC_011220 62 124/119 1.02E+08 292 100%
Footnotes:

  1. The Amplicon is the amplified piece of DNA which contains the Fwd, Rev and Probe sequence. Sequence between the Fwd, Rev and Probe are also included in Amplicon.
  2. The BLAST Score describes how similar the Amplicon sequence is to aligned sequences in the non-redundant GenBank Database. The range shown as High/Low reflects the highest and lowest scores for a pathogen that would generate a positive response using this assay.
  3. The number of sequences reviewed reflect the total number sequences in the non-redundant GenBank database on the date of the analysis. This number will change as new sequences are added to the GenBank database.
  4. Matches reflect the total number of pathogens identified in the BLAST search that would generate a positive ressponse. Statistically these are the number of True Positives (the diagnostic test would indicates the presence of the correct disease) = TP
  5. False positive (FP) – Test incorrectly detects the presence of pathogen in a sample that does not contain the pathogen. Shown as an incorrect pathogen in the BLAST analysis with a Score within the High/Low range listed for the assay.
    True negative (TN) – Test correctly identifies absence of pathogen. Calculated from BLAST data as the (total number of sequences reviewed) – (total number of pathogens correctly detected or TP).

Specificity = TN / TN + FP
https://lexjansen.com/nesug/nesug10/hl/hl07.pdf

* If you have inquiries about specific strains, please contact DTPM support.

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