Nail Fungal
Molecular Testing Kit

NAIL FUNGAL KIT

The DTPM Nail Fungal kit is specifically designed to test for pathogens in the aid of fast identification of nail fungal infections. Toenail or fingernail samples can be collected with no debridement of the nailbed needed.

SYMPTOMS TO CONSIDER:

Those patients affected may experience some of the following symptoms:

  • Thickened nails
  • Whiteish to yellow-brown discoloration
  • Brittle, crumbly, or ragged nail
  • A dark coloration or distorted shape
  • A new or odd odor

COLLECTION METHOD

The DTPM Nail Fungal kit utilizes a 3mm – 6mm (or larger) nail specimen collected by a healthcare professional.

ACCURACY AND QUICK RESULTS

The DTPM Nail Fungal Kit will allow your laboratory to provide healthcare professionals with the fastest and most accurate detection of common nail fungal organisms.

  • Expedited patient results
  • Multiple pathogens available
  • Unmatched accuracy of PCR
  • Simple collection
  • Direct access to experienced scientific staff
  • Personal customer service experience

For Research Use Only. Not for use In diagnostic procedures.

INTERESTED IN PARTNERING WITH US?

DTPM, Inc. is a nationwide provider of laboratory products, services, and solutions. DTPM has partnered with laboratories since 1993 to provide a comprehensive array of instrumentation, custom assays, laboratory consumables, supplies, and ongoing service and support.

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PATHOGENS DETECTED IN THE DTPM NAIL FUNGAL MOLECULAR TESTING KIT:

Pathogen Strain(s) Identified* Target Gene GenBank Accession Number Amplicon1 (base pairs) BLAST Score2 Range (High/Low) Sequences3 Reviewed Matches4 (True Positives) Specificity5
Acremonium (Sarocladium) strictum Acremonium (Sarocladium) strictum, S bactrocephalum, Sordariomycetes, Hypocreales, Lichtheimia corymbifera, Colletotrichum, Diaporthe eres, Valsa ambiens ITS Ribosomal NR_111145.1 121 239/200 1.02E+08 599 100%
Acremonium potronii Acremonium potronii, A dichromosporum, A fuci, A persicinum, A salmoneum, A sclerotigenum, A zonatum, Emericellopsis maritima, E alkalina, E cladophorae, E phycophila, E pallida, E stolkiae, E nidulans, E atlantica, Mycocitrus zonatus, Hypocreales, Parasarocladium breve, Stilbella fimetaria ITS Ribosomal JX535048.1 56 100/95 1.02E+08 219 100%
Alternaria species Alternaria species, Embellisia dennisii, E conoidea, E indefessa, Ulocladium dauci, U capsicum, U oudemansii, U obovoideum, septosporum, Nimbya perpunctulata, N perpunctulata, N celosiae Alta1 CM034651 84 147/110 1.02E+08 2441 100%
Aspergillus flavus / oryzae v2.0 Aspergillus flavus, A oryzae {*aflatoxin biosynthesis gene] aflC NC_054693.1 67 125/120 1.02E+08 47 100%
Aspergillus fumigatus Aspergillus fumigatus, A aculeatus, A arcoverdensis, A aureolus, A brevipes, A botucatensis, A chermesinum, A delicatus, A duricaulis, A felis, A fischeri, A frankstonensis, A fumigatiaffinis, A fumisynnematus, A hiratsukae, A igneus, A laciniosus, A lentulus, A malignus, A marvanovae, A nishimurae, A novofumigatus, A oerlinghausenensis, A parafelis, A pseudofelis, A pseudoviridinutans, A shendaweii, A siamensis, A spinosus, A takakii, A terrus, A tsunodae, A turcosus, A udagawae, A versicolor, A viridinutans, A waksmanii, A wyomingensis, Neosartorya aureola, N coreana, N fischeri, N hiratsukae, N laciniosa, N pseudofischeri, N spathulata, N spinosa, N udagawae, Penicillium chermesinum, P glandicola ITS Ribosomal NC_007197 101 193/181 1.02E+08 4220 100%
Aspergillus niger / tubingensis Aspergillus niger, A tubingensis, A aculeatus, A amstelodami, A awamori, A brasiliensis, A costaricensis, A cristatus, A ficuum, A foetidus, A lacticoffeatus, A luchuensis, A neoniger, A phoenicis, A piperis, A sclerotiorum, A terreus, A welwitschiae, Actinomucor elegans ITS Ribosomal CM033103 72 144/131 1.02E+08 5186 100%
Aspergillus terreus Aspergillus terreus, A alabamensis, A aureoterreus, A citrinoterreus, A elongatus A hortai, A jilinensis, A montoensis, A neoafricanus, A nomius, A pseudoterreus, A temulenta ITS Ribosomal LC496504 58 109/95 1.02E+08 1318 100%
Candida albicans Candida albicans, Candid dubliniensis Erg11 NC_032093 74 142/134 1.02E+08 363 100%
Candida parapsilosis Candida parapsilosis Erg11 NW_023503279 65 130/130 1.02E+08 502 100%
Candida tropicalis Candida tropicalis Erg11 NW_003020060 70 140/134 1.02E+08 369 100%
Epidermophyton floccosum Epidermophyton floccosum, Arthroderma uncinatum ITS Ribosomal MH858667.1 63 126/121 1.02E+08 166 100%
Fusarium solani Fusarium solani, F akasia, F ambrosium, F breve, F ensiforme, F euwallaceae, F falciforme, F ferrugineum, F haematococcum, F keratoplasticum, F lateritium, F lichenicola, F metavorans, F neocosmosporiellum, F oblongum, F oxysporum, F paranaense, F perseae, F petroliphilum, F phaseoli, F populicola, F pseudensiforme, F rekanum, F striatum, F suttonianum, F tonkinense, F vanettenii, F waltergamsii, F witzenhausenense, Earliella scabrosa, Ascomycota, Nectria haematococca, N ipomoeae, Neocosmospora vasinfecta, Sordariomycetes ITS Ribosomal KY484966.1 164 319/241 1.02E+08 10871 100%
Microsporum spp Microsporum canis, M ferrugineum, M audouinii, Arthroderma otae ITS Ribosomal LC317666 59 118/100 1.02E+08 965 100%
Nakaseomyces glabratus [previously Candida glabrata] Nakaseomyces glabratus previously known as Candida glabrata Erg11 NC_006028 64 128/128 1.02E+08 101 100%
Neofusicoccum mangiferae Neofusicoccum mangiferae, N eucalyptorum, N parvum, Botryosphaeria eucalyptorum ITS Ribosomal MN519717.1 80 157/148 1.02E+08 138 100%
Neoscytalidium (Scytalidium) dimidiatum Neoscytalidium (Scytalidium) dimidiatum, N novaehollandiae, N hyalinum, Botryosphaeria dothidea, Macrophomina phaseolina, Aureobasidium melanogenum, A namibiae, Arnium arizonense BT KF020895 54 105/90 1.02E+08 110 100%
Scopulariopsis brevicaulis Scopulariopsis brevicaulis, S alboflavescens, S cordiae, S flava, S insectivora, S stercoraria ITS Ribosomal LN850791.1 60 120/107 1.02E+08 136 100%
Trichophyton interdigitale / mentagrophytes Trichophyton interdigitale, T mentagrophytes, T benhamiae, T equinum, T indotineae, T quinckeanum, T tonsurans, T schoenleinii, T simii, T verrucosum, T violaceum, Arthroderma benhamiae, A simi, A vanbreuseghemii ITS Ribosomal NR_144900.1 65 130/108 1.02E+08 4066 100%
Trichophyton rubrum / soudanense Trichophyton rubrum, T soudanense, T gourvilii, T kuryangei, T raubitschekii, T violaceum, T yaoundei ITS Ribosomal NR_131330.1 64 128/104 1.02E+08 1873 100%
Footnotes:

  1. The Amplicon is the amplified piece of DNA which contains the Fwd, Rev and Probe sequence. Sequence between the Fwd, Rev and Probe are also included in Amplicon.
  2. The BLAST Score describes how similar the Amplicon sequence is to aligned sequences in the non-redundant GenBank Database. The range shown as High/Low reflects the highest and lowest scores for a pathogen that would generate a positive response using this assay.
  3. The number of sequences reviewed reflect the total number sequences in the non-redundant GenBank database on the date of the analysis. This number will change as new sequences are added to the GenBank database.
  4. Matches reflect the total number of pathogens identified in the BLAST search that would generate a positive ressponse. Statistically these are the number of True Positives (the diagnostic test would indicates the presence of the correct disease) = TP
  5. False positive (FP) – Test incorrectly detects the presence of pathogen in a sample that does not contain the pathogen. Shown as an incorrect pathogen in the BLAST analysis with a Score within the High/Low range listed for the assay.
    True negative (TN) – Test correctly identifies absence of pathogen. Calculated from BLAST data as the (total number of sequences reviewed) – (total number of pathogens correctly detected or TP).

Specificity = TN / TN + FP
https://lexjansen.com/nesug/nesug10/hl/hl07.pdf

* If you have inquiries about specific strains, please contact DTPM support.

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